LU201702对OVA诱发豚鼠急性支气管哮喘模型的研究文献综述

 2023-03-03 21:58:26

支气管哮喘发病机理及临床用药的研究进展

摘要:支气管哮喘是一种与气道高反应性相关的慢性气道炎症性疾病,中、西医都从其自身理论基础出发对其发病机制作出了概述,但其的发病机制复杂,至今尚未完全阐明。近年来随着对其发病机制分子水平的深入研究,哮喘的临床治疗已取得了很大的进步,大部分可以通过药物控制,进而不影响人们的正常生活。目前临床防止哮喘的最有效方法就是药物治疗,常用药物包括糖皮质激素、beta;2肾上腺素受体激动剂、茶碱类、M胆碱受体阻断药和抗白三烯药等。现就支气管哮喘发病理及临床用药的研究进展作一综述。

关键词:支气管哮喘;发病机制;药物治疗;综述

Abstract: Bronchial asthma is a chronic inflammatory disease associated with airway hyperresponsiveness.Chinese and Western medicine have made an overview of its pathogenesis from its own theoretical basis, but its pathogenesis is complex, has not yet been fully clarified.In recent years, with the in-depth study of the molecular mechanism of its pathogenesis, the clinical treatment of asthma has made great progress, most of which can be controlled by drugs, and thus does not affect peoples normal life.The most effective way to prevent clinical asthma is drug treatment, commonly used drugs include corticosteroids, beta 2 adrenergic receptor agonist, theophylline, M cholinergic receptor blockers and anti leukotriene drugs.This article reviews the research progress of the pathology and clinical medication of bronchial asthma.

Key Words:bronchial asthma;Pathogenesis;Medication;Overview

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